Effect of non-symmetric waveform on conduction block induced by high-frequency (kHz) biphasic stimulation in unmyelinated axon
نویسندگان
چکیده
منابع مشابه
Conduction block in myelinated axons induced by high-frequency (kHz) non-symmetric biphasic stimulation
This study used the Frankenhaeuser-Huxley axonal model to analyze the effects of non-symmetric waveforms on conduction block of myelinated axons induced by high-frequency (10-300 kHz) biphasic electrical stimulation. The results predict a monotonic relationship between block threshold and stimulation frequency for symmetric waveform and a non-monotonic relationship for non-symmetric waveforms. ...
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The effect of a non-symmetric waveform on nerve conduction block induced by high-frequency biphasic stimulation is investigated using a lumped circuit model of the unmyelinated axon based on Hodgkin-Huxley equations. The simulation results reveal that the block threshold monotonically increases with the stimulation frequency for the symmetric stimulation waveform. However, a nonmonotonic relati...
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Introduction Abnormal neural impulses in the nervous system may lead to various diseases and disabilities. High frequency alternating currents (HFAC) has been used to block the propagation of such impulses and improve the symptoms or disabilities. The technique is safe, reversible, and relatively selective, and its reliability, the optimum stimulation parameters, and elimination of the onset re...
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introduction: high frequency alternating currents is a safe, reversible and selective method for nerve conduction block that has been under study during the last decade as a treatment for the diseases involving abnormal neural impulses. however, reducing the stimulus amplitude, and the undesired onset response, as well as optimizing the stimulus parameters for more effective block is still unde...
متن کاملasymmetric rectangular waveform in stimulation with high frequency alternating current reduces the threshold for neural conduction block
introduction abnormal neural impulses in the nervous system may lead to various diseases and disabilities. high frequency alternating currents (hfac) has been used to block the propagation of such impulses and improve the symptoms or disabilities. the technique is safe, reversible, and relatively selective, and its reliability, the optimum stimulation parameters, and elimination of the onset re...
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ژورنال
عنوان ژورنال: Journal of Computational Neuroscience
سال: 2014
ISSN: 0929-5313,1573-6873
DOI: 10.1007/s10827-014-0510-z