Effect of Polysorbate 80 on Oritavancin Binding to Plastic Surfaces: Implications for Susceptibility Testing
نویسندگان
چکیده
منابع مشابه
Effect of polysorbate 80 on oritavancin binding to plastic surfaces: implications for susceptibility testing.
Oritavancin, a semisynthetic lipoglycopeptide with activity against gram-positive bacteria, has multiple mechanisms of action, including the inhibition of cell wall synthesis and the perturbation of the membrane potential. Approved guidelines for broth microdilution MIC assays with dalbavancin, another lipoglycopeptide, require inclusion of 0.002% polysorbate 80. To investigate the potential im...
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Effect of Polysorbate-80 on Oritavancin Binding to Plastic Surfaces – 1 Implications for Susceptibility Testing 2 3 4 Running Title: Polysorbate-80 effect on oritavancin binding 5 6 7 Francis F. Arhin 1 , Ingrid Sarmiento 1 , Adam Belley 1 , Geoffrey A. M c Kay 1 , Deborah C. Draghi 2 , 8 Parveen Grover 2 , Daniel F. Sahm 2 , Thomas R. Parr Jr. 1 and Gregory Moeck 1* 9 10 Targanta Therapeutics,...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2008
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01513-07