Effectiveness of D-dimer and heart-type fatty acid-binding protein as tools for diagnosis of myocardial infraction
نویسندگان
چکیده
Background: The role of D-dimer and H-FABP as diagnostic markers in myocardial infarction (MI) is still a question. We aim to investigate the usefulness determination for evaluation patients. Methods: Forty patients with MI 40 controls mean age (57.37 ± 8.27), (57.47±8.329) were conducted. D-dimer, H-FABP, troponin I tests determinate at admission using Up-Converting Phosphor Quantitative Immunoassay Analyzer.Results: D-Dimer concentrations greater significantly than controls, was cTnI level (P < 0.001). cut-off values diagnosis 425ng/ml, 4.1 ng/ml, 0.105 ng/ml respectively with. sensitivity specificity 82.5.% 65.0%, it 77.5%, 57.5% 82.5% 62.5%, MI.Conclusions: biomarker early would be ideal combination cover complete MI.
منابع مشابه
Heart-type fatty acid-binding protein in the early diagnosis of acute myocardial infarction.
OBJECTIVE To investigate the diagnostic and prognostic role of heart-type fatty acid-binding protein (hFABP) compared with copeptin and in addition to high-sensitivity cardiac troponin T (hs-cTnT) in patients with chest pain suspected of acute myocardial infarction (AMI). DESIGN Diagnostic and prognostic performances of hFABP, copeptin and hs-cTnT were evaluated and compared. The final diagno...
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We hypothesized that when used in combination with cardiac troponins, heart-type fatty acid binding protein (H-FABP) would have greater diagnostic value than conventional markers for the early diagnosis of myocardial infarction (MI). Patients with typical chest pain at a single emergency department were consecutively enrolled. Initial blood samples were drawn for H-FABP, myoglobin, creatine kin...
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Objective: Exercise and nutrition as life style modification strategies for the prevention and control of diabetes are considered. The aim of present study was to assess the effects of saffron consumption and aerobic exercises on serum levels of Heart-type fatty acid binding protein (HFABP) and Troponin T in type2 diabetes (T2DM) patients. Materials and Methods: This study was a quasi-experime...
متن کاملHeart-type fatty acid-binding protein in the early diagnosis of acute myocardial infarction: a systematic review and meta-analysis
Objective To determine the accuracy of heart-type fatty acid-binding protein (H-FABP) as a new and early cardiac biomarker in the early diagnosis of acute myocardial infarction (AMI). The introduction of early and safe biomarkers could lead to (a) a large reduction in unnecessary hospital referrals of patients suspected of, but not, having AMI and (b) an earlier start of treatment in patients w...
متن کاملMeasurement of heart-type fatty acid-binding protein before discharge.
plasm of cardiomyocytes. Therefore, H-FABP is released more quickly than the troponins into the circulation when membrane integrity is compromised in response to myocardial injury. Levels of H-FABP are detectable as early as 2–3 h and typically return to baseline levels within 12–24 h of the initial insult.9,10 Consistent with these findings, a growing number of studies have shown that H-FABP i...
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ژورنال
عنوان ژورنال: International journal of advanced biochemistry research
سال: 2023
ISSN: ['2617-4693', '2617-4707']
DOI: https://doi.org/10.33545/26174693.2023.v7.i1a.167