Effectiveness of Sofosbuvir and Velpatasvir Combination in Chronic Hapatitis C

Objective: The purpose of this research is to evaluate the efficacy a combination medication consisting sofosbuvir and velpatasvir in treating individuals with chronic hepatitis C. Study Design: Observational/ Prospective study Place Duration: Conducted at Department Gastroenterology Mayo Hospital Lahore, during from period Feb 2021 Jan 2022. Methods: There were 67 participants study. patients' ages ranged 18 70. We gathered demographic information about patient, such as age, gender, height, weight, after getting written consent. Hepatitis C patients known genotypes shown. A SOF/VLP regimen containing was administered for total 12 weeks. entire set data examined using SPSS 18.0. Results: In current study, 42 (62.7%) males 25 (37.3%). Included had mean age 31.12±15.80 years BMI 24.7±8.34 kg/m2. found that rate higher 63 (94.03%) cases. As per laboratory findings, aspartate aminotransferase (AST) 37.5± 11.21, alanine (ALT) 26.2±6.44, haemoglobin level 12.24±10.17 all showed considerable improvement therapy. Most common adverse outcomes headache 35 (52.2%), fatigue 22 (32.8%) nausea 10 (14.9%). Conclusion: or without cirrhosis, regardless HCV genotype, has shown be extremely successful infection. This true genotype. Keywords:, C, Sofosbuvir, Comorbidities, Velpatasvir,