Effects of 2-chloroadenosine on isolated perfused rabbit ear artery
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چکیده
منابع مشابه
Ectopic Beats in Isolated Perfused Rabbit Hearts
Heart vector location was estimated for 23 isolated, perfused rabbit hearts during paced ectopic beats. Twenty computer-processed signals, derived from the surface electrodes of a spherical electrolyte-filled tank containing the hearts, were optimally fitted with a locatable cardiac dipole every millisecond of the QRS and every 3rd msec of the ST-T interval. During the QRS, the computed heart v...
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The isolated perfused lung (IPL), when compared to available in vitro and in vivo pulmonary systems, is a preparation that fulfills a majority of the ideal criteria for studying metabolism, binding and/or physiological response to xenobiotics. The IPL is an exceptionally useful method when there is a need for concurrent administration of multiple agents in different physical forms. Various deta...
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The mechanical effects of ischemic contracture may be important in the development of irreversible cellular damage as it increases mechanical stress on sarcolemmal membranes and restricts endocardial perfusion. To assess the relative importance of these mechanical effects compared with decreased energy supply in the development of irreversible injury, the effects of inhibiting ischemic contract...
متن کاملBiphasic vasoconstriction of the rabbit ear artery.
Sympathetic nerve stimulation and intralummal norepinephrine infusion for more than 15 seconds produced a biphasic response in the isolated rabbit ear artery perfused with RREBS solution. This response consisted of an initial rapid constriction (phase A), which was followed by partial relaxation, and a final slowly developing constriction (phase B), which lasted for the duration of nerve stimul...
متن کاملComparative cardiac effects of terlipressin, vasopressin, and norepinephrine on an isolated perfused rabbit heart.
BACKGROUND Terlipressin, a synthetic analog of arginine-vasopressin (AVP), has been proposed as an effective vasopressive therapy in catecholamine-resistant vasodilatory shock. Although beneficial effects of terlipressin on systemic arterial pressure have been clearly demonstrated, its intrinsic effects on coronary circulation and myocardial performances remain unknown. METHODS The authors co...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1986
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)59254-x