Effects of -Aminobutyric AcidA Receptor Manipulation on Migrating Gonadotropin-Releasing Hormone Neurons through the Entire Migratory Route in Vivo and in Vitro
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چکیده
منابع مشابه
The effects of supraphysiological levels of testosterone on neural networks upstream of gonadotropin-releasing hormone neurons
Objective(s): Several pathological conditions are associated with hyper-production of testosterone; however, its impacts are not well understood. Hence, we evaluated the effects of supraphysiological levels of testosterone on gonadotropin-releasing hormone (GnRH) system in the hypothalamus of male rats. Also, we assessed the expression of two excitatory (kisspeptin and...
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15 صفحه اولDiurnal in vivo and rapid in vitro effects of estradiol on voltage-gated calcium channels in gonadotropin-releasing hormone neurons.
A robust surge of gonadotropin-releasing hormone (GnRH) release triggers the luteinizing hormone surge that induces ovulation. The GnRH surge is attributable to estradiol feedback, but the mechanisms are incompletely understood. Voltage-gated calcium channels (VGCCs) regulate hormone release and neuronal excitability, and may be part of the surge-generating mechanism. We examined VGCCs of GnRH ...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2000
ISSN: 0013-7227
DOI: 10.1210/en.141.3.1254