Effects of Clonidine Withdrawal: Possible Mechanisms and Suggestions for Management
نویسندگان
چکیده
منابع مشابه
Effects of clonidine withdrawal: possible mechanisms and suggestions for management.
A severe rebound rise in blood pressure with agitation and insomnia had been noted in five patients when they had previously ceased clonidine (Catapres) This has been shown to be reproducible in these patients and to be associated with a significant increase in urinary catecholamine excretion. The blood pressure can be controlled and the symptoms alleviated promptly by alpha and beta adrenergic...
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C lonidine is an imidazoline derivative with antihypertensive properties. Its mode of action is complex and is as yet not fully understood. Some datal-‘j indicate that an action on the central nervous system, predominantly at bulbar and diencephalic levels, causes a decreased sympathetic outflow to the cardiovascular system. Other studies’ show a direct peripheral effect as well. Since the intr...
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ژورنال
عنوان ژورنال: BMJ
سال: 1973
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5860.209