Effects of Digitalis on Myocardial Ionic Exchange

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Effects of digitalis on myocardial ionic exchange.

SUMMARY Prior to consideration of the effects of digitalis compounds on ionic exchange the basic mechanisms of active Na+ and K+ transport are discussed. It is generally accepted that digitalis is a specific inhibitor of the Na+-K+ activated ATPase located primarily in the sarcolemmal membrane. Present evidence supports the concept that positive inotropic effects of digitalis are not seen unles...

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ژورنال

عنوان ژورنال: Circulation

سال: 1972

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.46.1.180