Efficacy of tiotropium–olodaterol fixed-dose combination in COPD
نویسندگان
چکیده
منابع مشابه
Efficacy of tiotropium–olodaterol fixed-dose combination in COPD
Tiotropium-olodaterol, formulated in the Respimat soft-mist inhaler, is an inhaled fixed-dose combination (FDC) of a long-acting muscarinic antagonist (LAMA) and a long-acting β2-agonist (LABA), commercialized under the name of Spiolto or Stiolto. The efficacy of tiotropium-olodaterol 5-5 μg once daily in adult patients with COPD was documented in eleven large, multicenter trials of up to 52 we...
متن کاملAdvantages of Efficacy and Safety of Fixed-Dose Tafluprost/Timolol Combination Over Fixed-Dose Latanoprost/Timolol Combination
PURPOSE To compare the safety and efficacy of fixed-dose tafluprost/timolol combination (Taf/T-FDC) with those of fixed-dose latanoprost/timolol combination (Lat/T-FDC) by measuring the intraocular pressure (IOP)-lowering effect, ocular pharmacokinetics, and ocular surface toxicity. METHODS The IOP-lowering effect of Taf/T-FDC and Lat/T-FDC in ocular normotensive monkeys was evaluated at 4 an...
متن کاملFixed-dose combination Therapy in Hypertension: Focus on Fixed-dose combination of Amlodipine and Valsartan (exforge®)
Hypertension is the leading cause of disability and cardiovascular mortality world-wide. Approximately one-third of the US adult population and over a billion people world-wide have hypertension. Despite increased awareness of hypertension and availability of many effective antihypertensive agents, only one third of patients achieve their target blood pressure (BP). All expert panels now recomm...
متن کاملTiotropium and olodaterol fixed-dose combination versus mono-components in COPD (GOLD 2–4)
Efficacy and safety of tiotropium+olodaterol fixed-dose combination (FDC) compared with the mono-components was evaluated in patients with moderate to very severe chronic obstructive pulmonary disease (COPD) in two replicate, randomised, double-blind, parallel-group, multicentre, phase III trials. Patients received tiotropium+olodaterol FDC 2.5/5 μg or 5/5 μg, tiotropium 2.5 μg or 5 μg, or olod...
متن کاملEfficacy and Safety of a Lercanidipine/Enalapril Fixed-Dose Combination in Hypertensive Patients in Portugal
BACKGROUND Fixed-dose combinations of hypertensive drugs have been advocated as a suitable option for hypertensive patients who require two or more drugs to achieve blood pressure (BP) targets. OBJECTIVES Our objective was to assess the efficacy and safety of lercanidipine/enalapril in clinical practice. METHODS This observational study collected data for patients with hypertension treated ...
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ژورنال
عنوان ژورنال: International Journal of Chronic Obstructive Pulmonary Disease
سال: 2016
ISSN: 1178-2005
DOI: 10.2147/copd.s92840