Efficient transduction of melanoma cells with Sendai viral vectors
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چکیده
منابع مشابه
Efficient gene delivery and selective transduction of astrocytes in the mammalian brain using viral vectors
Astrocytes are now considered as key players in brain information processing because of their newly discovered roles in synapse formation and plasticity, energy metabolism and blood flow regulation. However, our understanding of astrocyte function is still fragmented compared to other brain cell types. A better appreciation of the biology of astrocytes requires the development of tools to gener...
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We have examined the ability of recombinant adenoviral vectors to transduce human hematopoietic cells. Our findings indicate that adenovirus readily infects a large proportion of CD34+ cells. Using adenovirus vectors that transduce either a lacZ or an alkaline phosphatase reporter gene, we observed up to 45% of total CD34+ cells infected. Upon more detailed analysis, we observed comparable leve...
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BACKGROUND For both in vitro and in vivo gene transfer applications, recombinant viral vectors have almost always been used free in solution. Some site-specificity of the delivery of viral vectors can be achieved by applying a solution containing viral particles specifically to the site of interest. However, such site-specificity is seriously limited since viral vectors can diffuse freely in so...
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ژورنال
عنوان ژورنال: Turkish Bulletin of Hygiene and Experimental Biology
سال: 2017
ISSN: 0377-9777,1308-2523
DOI: 10.5505/turkhijyen.2017.98705