Electrophysiological sequels of inflammatory demyelination.
نویسندگان
چکیده
منابع مشابه
Electrophysiological and Histological Study of Lysolecithin-Induced Local Demyelination in Adult Mice Optic Chiasm
Introduction: Demyelination is one of the main causes of neurological disability. It is the end product of numerous pathological processes, multiple sclerosis (MS) being the most common cause. More than 70% of the MS patients suffer from optic disturbances. This disease commonly affects the optic pathway, particularly the optic nerves and chiasm. Several attempts have been made to produce a ...
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Multiple sclerosis is characterized by inflammatory demyelination and irreversible axonal injury leading to permanent neurological disabilities. Diffusion tensor imaging demonstrates an improved capability over standard magnetic resonance imaging to differentiate axon from myelin pathologies. However, the increased cellularity and vasogenic oedema associated with inflammation cannot be detected...
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OBJECTIVES Multiple Sclerosis (MS) is a disease that affects the Central Nervous System by destructing myelin shield and also can affects the peripheral nervous system. Demyelination is acquired characteristics disease and appears with the degeneration of myelin which protects the axons. Cuprizone (CPZ) model is a toxic demyelination model. The purpose of this study was to develop an MS model b...
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BACKGROUND Cortical disease has emerged as a critical aspect of the pathogenesis of multiple sclerosis, being associated with disease progression and cognitive impairment. Most studies of cortical lesions have focused on autopsy findings in patients with long-standing, chronic, progressive multiple sclerosis, and the noninflammatory nature of these lesions has been emphasized. Magnetic resonanc...
متن کاملelectrophysiological and histological study of lysolecithin-induced local demyelination in adult mice optic chiasm
introduction: demyelination is one of the main causes of neurological disability. it is the end product of numerous pathological processes, multiple sclerosis (ms) being the most common cause. more than 70% of the ms patients suffer from optic disturbances. this disease commonly affects the optic pathway, particularly the optic nerves and chiasm. several attempts have been made to produce a sui...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1994
ISSN: 0022-3050
DOI: 10.1136/jnnp.57.suppl.29