Embarking on antidepressant response prediction using brain perfusion estimation
نویسندگان
چکیده
منابع مشابه
Effects of antidepressant treatment with rTMS and fluoxetine on brain perfusion in PD.
BACKGROUND Although depression is highly prevalent in Parkinson disease (PD), little is known about the neural correlates associated with depression and antidepressant treatment in PD. OBJECTIVE To examine the effects of fluoxetine and repetitive transcranial magnetic stimulation (rTMS) on regional cerebral blood flow (rCBF) using SPECT in patients with PD and depression. METHODS Twenty-six...
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Current treatment of Major Depressive Disorder utilizes a trial-and-error sequential treatment strategy that results in delays in achieving response and remission for a majority of patients. Protracted ineffective treatment prolongs patient suffering and increases health care costs. In addition, long and unsuccessful antidepressant trials may diminish patient expectations, reinforce negative co...
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1. Gupta et al have proposed a 9% depression attenuation separator to differentiate potential responders from potential non responders. This separator is small and is intuitively not logical; for example, a 10% figure would have made m&re sense. The choice of a non-intuitive figure suggests that the separation between responders and non responders was very narrow. In other words, response to th...
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Natural language (NL) user interfaces are growing in popularity. Unfortunately, the complexity of NL interaction makes these interfaces difficult to design. For NL interfaces to become successful, universal tools are needed to help support the NL design process. What work practice should these tools explicitly support? Interviews with NL designers and our own experiments have identified a speci...
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BACKGROUND AND PURPOSE We have developed a dynamic CT method to measure absolute cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT). In this study we evaluated the ability of CT-derived functional maps to detect infarction in a rabbit model of focal cerebral ischemia. METHODS Sequential dynamic CT studies were performed at 2 different slices in 5 control rabbi...
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ژورنال
عنوان ژورنال: EClinicalMedicine
سال: 2019
ISSN: 2589-5370
DOI: 10.1016/j.eclinm.2019.04.008