Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor
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چکیده
منابع مشابه
Stabilizing volatile liquid chemicals using co-crystallization.
A convenient, effective, and scalable protocol for stabilizing volatile liquid chemicals is reported. Through the use of halogen-bond driven co-crystal synthesis, several examples of liquid iodoperfluoroalkanes are transformed into crystalline materials with low-vapor pressure, considerable thermal stability, and moisture resistance. The target compounds can subsequently be re-generated through...
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Volume 1 • Issue 4 • 1000e111 J Pharmacovigilance ISSN: 2329-6887 JP, an open access journal In today’s world where life is fast-paced, public health is a big concern. With the tremendous ongoing development in the field of pharmaceutical drugs, people can find cure for a vast variety of diseases. These modern-day medicines have been proven to be more effective in treating, managing, controllin...
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ژورنال
عنوان ژورنال: BMC Structural Biology
سال: 2012
ISSN: 1472-6807
DOI: 10.1186/1472-6807-12-22