Enantiospecific synthesis of functionalised bicyclo[3.3.1]nonanes from 10-bromocarvones via tandem intermolecular alkylation-intramolecular Michael addition sequence
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چکیده
منابع مشابه
Enantioselective synthesis of benzoindolizidine derivatives using chiral phase-transfer catalytic intramolecular domino aza-Michael addition/alkylation.
An efficient and enantioselective strategy to synthesize benzoindolizidines from α,β-unsaturated amino ketones via domino intramolecular aza-Michael addition/alkylation was developed. These reactions were enabled by cinchona alkaloid-derived quaternary ammonium salts as the phase-transfer catalyst. A variety of benzoindolizidines were prepared in good yields (up to 93%) and enantioselectivities...
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2003
ISSN: 1551-7012
DOI: 10.3998/ark.5550190.0004.307