Endogenous Nodal signaling regulates germ cell potency during mammalian testis development
نویسندگان
چکیده
منابع مشابه
Endogenous Nodal signaling regulates germ cell potency during mammalian testis development.
Germ cells, the embryonic precursors of sperm or oocytes, respond to molecular cues that regulate their sex-specific development in the fetal gonads. In males in particular, the balance between continued proliferation and cell fate commitment is crucial: defects in proliferation result in insufficient spermatogonial stem cells for fertility, but escape from commitment and prolonged pluripotency...
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ژورنال
عنوان ژورنال: Development
سال: 2012
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.083006