Endothelial cell mitogens derived from retina and hypothalamus: biochemical and biological similarities.
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چکیده
منابع مشابه
Endothelial cell mitogens derived from retina and hypothalamus: biochemical and biological similarities
Bovine retina and hypothalamus contain anionic endothelial cell mitogens that display unusual affinities for the negatively charged glycosaminoglycan heparin. Both growth factor activities are acidic polypeptides (pl's of 5.0) as determined by isoelectric focusing and DEAE-affinity chromatography. In spite of their anionic nature, the factors bound to heparin-Sepharose columns with high affinit...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1984
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.99.4.1545