Endothelial dysfunction in patients with non-ST-segment elevation myocardial infarction

Purpose: Evaluation of peripheral endothelial function using EndoPAT 2000 device in patients with non-ST-elevation myocardial infarction (NSTEMI) and correlation clinical characteristics the patients. Material methods: The study included 39 NSTEMI, hospitalized 2 PCI centers, period 03.2022-03.2023. At 72 hours after admission, was assessed device. Patients were divided into groups according to presence dysfunction (RHI <1.67). Statistical analysis data performed t-test χ2 test. Results: average value reactive hyperemia index (RHI) 1.73 ± 0.47. Endothelial diagnosed 51,3% NSTEMI Group I 19 normal (RHI>1.67), group II – 20 (RHI<1.67). In dysfunction, two- or three-vessel disease prevailed (χ2=2.7, p=0.43) a higher rate coronary angioplasty recorded (χ2=4.36, p=0.037). Conclusion: Peripheral estimated by EndoPat method is identified NSTEMI. correlated severity lesions. Further studies are needed assess diagnostic prognostic method.