Engineering higher affinity T cell receptors using a T cell display system
نویسندگان
چکیده
منابع مشابه
Breaking the affinity ceiling for antibodies and T cell receptors.
PNAS u September 26, 2000 u vol. 97 u no. 20 u 10679–10681 The antigen receptors made by lymphocytes are antibodies, which exist as soluble and cell-bound molecules, and Tcell receptors (TCRs), which are always found on cell surfaces. The function of these receptors in immunity depends on their specificity and affinity for antigen. Specificity—the potential to bind one unique chemical structure...
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ژورنال
عنوان ژورنال: Journal of Immunological Methods
سال: 2008
ISSN: 0022-1759
DOI: 10.1016/j.jim.2008.09.016