Engineering of complex protein sialylation in plants
نویسندگان
چکیده
منابع مشابه
Engineering of complex protein sialylation in plants.
Sialic acids (Sias) are abundant terminal modifications of protein-linked glycans. A unique feature of Sia, compared with other monosaccharides, is the formation of linear homo-polymers, with its most complex form polysialic acid (polySia). Sia and polySia mediate diverse biological functions and have great potential for therapeutic use. However, technological hurdles in producing defined prote...
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This research tends to development of the requirements elicitation methodology with regard to operational nature and hierarchical analysis for complex systems and also, regarding available technologies. This methodology applies Analytic Hierarchy Process (AHP) and Analytic Network Process (ANP) to ensure traceability of planned qualitative and quantitative data from requirements to available te...
متن کاملRequirements Engineering Model in Designing Complex Systems
This research tends to development of the requirements elicitation methodology with regard to operational nature and hierarchical analysis for complex systems and also, regarding available technologies. This methodology applies Analytic Hierarchy Process (AHP) and Analytic Network Process (ANP) to ensure traceability of planned qualitative and quantitative data from requirements to available te...
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Protein sialylation by sialyltransferase involves radiation resistance.
Previously, we identified beta-galactoside alpha(2,6)-sialyltransferase (ST6Gal I) as a candidate biomarker for ionizing radiation. The expression of ST6Gal I and the level of protein sialylation increased following radiation exposure in a dose-dependent manner. Radiation induced ST6Gal I cleavage and the cleaved form of ST6Gal I was soluble and secreted. Sialylation of integrin beta1, a glycos...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2016
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1604371113