Enhancing De Novo Transcriptome Assembly by Incorporating Multiple Overlap Sizes
نویسندگان
چکیده
منابع مشابه
Enhancing De Novo Transcriptome Assembly by Incorporating Multiple Overlap Sizes
Background. The emergence of next-generation sequencing platform gives rise to a new generation of assembly algorithms. Compared with the Sanger sequencing data, the next-generation sequence data present shorter reads, higher coverage depth, and different error profiles. These features bring new challenging issues for de novo transcriptome assembly. Methodology. To explore the influence of thes...
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Given the importance of transcriptome analysis in various biological studies and considering thevast amount of whole transcriptome sequencing data, it seems necessary to develop analgorithm to assemble transcriptome data. In this study we propose an algorithm fortranscriptome assembly in the absence of a reference genome. First, the contiguous sequencesare generated using de Bruijn graph with d...
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given the importance of transcriptome analysis in various biological studies and considering thevast amount of whole transcriptome sequencing data, it seems necessary to develop analgorithm to assemble transcriptome data. in this study we propose an algorithm fortranscriptome assembly in the absence of a reference genome. first, the contiguous sequencesare generated using de bruijn graph with d...
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ژورنال
عنوان ژورنال: ISRN Bioinformatics
سال: 2012
ISSN: 2090-7346
DOI: 10.5402/2012/816402