Enigma of Bilirubin Conjugation
نویسندگان
چکیده
منابع مشابه
Bilirubin Conjugation by Human Liver
Adlard, B. P. F., and Lathe, G. H. (1970). Archives of Disease in Childhood, 45, 186. Breast milk jaundice: effect of 3oc,20,B-pregnanediol on bilirubin conjugation by human liver. The effect of 3ot,20fl-pregnanediol and other steroids on bilirubin conjugation was examined using liver tissue from human and four other species. Neither 3Ix,20fl-pregnanediol nor 3a,200c-pregnanediol inhibited conj...
متن کاملEffect of fatty acids on bilirubin conjugation.
Hargreaves, T. (1973). Archives of Disease in Childhood, 48, 446. Effect of fatty acids on bilirubin conjugation. The effect of fatty acids on bilirubin conjugation has been studied. Unsaturated fatty acids containing 18 to 20 carbon atoms decreased the rate of conjugation in rat liver slices and microsomes, probably by inhibiting glucuronyl transferase. Since fatty acids may be an important so...
متن کاملBilirubin excretion in rats with normal and impaired bilirubin conjugation: effect of phenobarbital.
The effect of phenobarbital on bilirubin excretion was studied in rats with different capacities for bilirubin conjugation. Drug treatment induced substantial increases in bilirubin UDP-glucuronyl transferase activity in the liver of both normal and heterozygous Gunn rats, but not homozygous Gunn rats in which enzyme activity is completely absent. However, enhancement of bilirubin excretion in ...
متن کاملHormonal control of hepatic bilirubin transport and conjugation.
GARTNER, LAWRENCE M., AND IRWIN M. ARIAS. Hormonal control of hepatic bilirubin transport and conjugation. Am. J. Physiol. 222(5): 1091-1099. 1972. -The role of the pituitary and thyroid glands in the regulation of hepatic transport and metabolism of bilirubin in Sprague-Dawley rats was investigated with continuous bilirubin infusion and bile collection for estimation of cumulative hepatic upta...
متن کاملBreast milk bilirubin conjugation inhibitors in neonatal hyperbilirubinaemia.
Sir, We were interested to read the observations of Cole and Hargreaves (1972) on Conjugation Inhibitors and Early Neonatal Hyperbilirubinaemia. We, also, were unable to find a correlation between the serum bilirubin concentration in breastfed, 6-day-old infants and conjugation inhibitors in the mother's milk (Arthur, Bevan, and Holton, 1966). However, it would be wrong to conclude that breast ...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1971
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(19)33605-4