EphrinA1 Is Released in Three Forms from Cancer Cells by Matrix Metalloproteases
نویسندگان
چکیده
منابع مشابه
The inhibition of matrix metalloproteases by tissue inhibitors of metalloproteases revealed by X-ray crystallography.
B , Rezmkoff, W , Riley, M , Schaechter, M and Umbarger, H E eds ) 419-428, American Society for Microbiology, Washington DC Lewis M , et al and Lu P (1996) Crystal structure of the lactose operon repressor and its complexes with DNA and mducei Science 271 , 1247-1254 Schell M A (1993) Molecular biology of the LysR family of transcriptional regulators Annu Re\ Microbiol 47, 597-626 Schumacher M...
متن کاملHistorical perspective of matrix metalloproteases.
Matrix metalloproteinases (MMPs) were identified as early as 1962. Since this seminal finding, this family of zinc-dependent endopeptidases has been studied extensively. This collective work has resulted in delineation of MMP gene and protein structures, the mechanisms of control of MMPs, the action of MMPs on both extracellular matrices and other proteins such as growth factors and cytokines, ...
متن کاملGlucose Inhibition of Glucagon Secretion From Rat -Cells Is Mediated by GABA Released From Neighboring -Cells
-Aminobutyric acid (GABA) has been proposed to function as a paracrine signaling molecule in islets of Langerhans. We have shown that rat -cells release GABA by Ca -dependent exocytosis of synaptic-like microvesicles. Here we demonstrate that GABA thus released can diffuse over sufficient distances within the islet interstitium to activate GABAA receptors in neighboring cells. Confocal immunocy...
متن کاملMatrix metalloproteases and lung disease.
healing are just some of the physiological processes in which the matrix metalloproteases (MMPs), a family of highly homologous endo-peptidases, play a crucial part.'" Collectively the MMPs can cleave most, if not all, the protein constituents of the extracellular matrix including collagen, proteoglycan, laminin, fibronectin, and elastin. In so doing they facilitate cell movement, reorientation...
متن کاملMatrix metalloproteases and PAR1 activation.
Cardiovascular diseases, including atherothrombosis, are the leading cause of morbidity and mortality in the United States, Europe, and the developed world. Matrix metalloproteases (MMPs) have recently emerged as important mediators of platelet and endothelial function, and atherothrombotic disease. Protease-activated receptor-1 (PAR1) is a G protein-coupled receptor that is classically activat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2012
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.06791-11