Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity
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چکیده
منابع مشابه
Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity
Synapsin I (SynI) is a synaptic vesicle (SV) phosphoprotein playing multiple roles in synaptic transmission and plasticity by differentially affecting crucial steps of SV trafficking in excitatory and inhibitory synapses. SynI knockout (KO) mice are epileptic, and nonsense and missense mutations in the human SYN1 gene have a causal role in idiopathic epilepsy and autism. To get insights into th...
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ژورنال
عنوان ژورنال: Human Molecular Genetics
سال: 2013
ISSN: 1460-2083,0964-6906
DOI: 10.1093/hmg/ddt071