Epinephele jurtina L. ab. semialba Brd

Results of the BRD CAP project: progress toward identifying genetic markers associated with BRD susceptibility.

The Bovine Respiratory Disease Coordinated Agricultural Project (BRD CAP) is a 5-year project funded by the United States Department of Agriculture (USDA), with an overriding objective to use the tools of modern genomics to identify cattle that are less susceptible to BRD. To do this, two large genome wide association studies (GWAS) were conducted using a case:control design on preweaned Holste...

Allozyme variation in the butterfly, Maniala jurtina (Lepidoptera: Satyrinae) (L.): evidence for selection

This paper describes patterns of allozyme variation in the butterfly, Maniola jurtina (L.). Twelve loci, of which four were polymorphic (PGM, PGI, IDH-l and IDH-2), were screened across 14 populations in south-east England. The patterns described are not in agreement with expectation for a sedentary butterfly in which alleles are neutral to selection, for geographically distant populations diff...

Anticoagulant Administration after Cardiac Infarction BrD

5-10% but was sometimes found when the level was 10-25%. Though relating to a different therapeutic problem their results may be relevant. The average daily dose of 72 mg. of phenindione in this trial was less than the mean daily dose of 108 mg. used in the M.R.C. long-term anticoagulant trial (Report to Medical Research Council, 1959, 1964). The moderate anticoagulant effect might explain the ...

BRD 3 / 4 inhibition and FLT 3 -

In the present work we aimed to identify targetable signaling networks in human MLL-AF9 leukemias. We show that MLL-AF9 cells critically depend on FLT3-ligand induced pathways as well as on BRD3/4 for their survival. We evaluated the in vitro and in vivo efficacy of the BRD3/4 inhibitor I-BET151 in various human MLL-AF9 (primary) models and patient samples and analyzed the transcriptome changes...

BRD 4 ( bromodomain containing 4 ) Anna