Erectile Dysfunction in a Murine Model of Sleep Apnea

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Erectile dysfunction in a murine model of sleep apnea.

RATIONALE Erectile dysfunction (ED) is frequent in obstructive sleep apnea syndrome (OSAS). Chronic intermittent hypoxia (CIH), one of the hallmarks of OSAS, could mediate ED. OBJECTIVES To determine whether intermittent hypoxia during sleep affects erectile dysfunction in mice. METHODS Three groups of C57BL/6 mice were exposed to CIH for 5 or 24 weeks. Sexual function was evaluated by in v...

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[Obstructive sleep apnea and erectile dysfunction].

Erectile dysfunction (ED) is common among men with obstructive sleep apnea (OSA) with reports of prevalence varying from 30 – 50 percent. The mechanism is unknown. Since chronic hypoxia is known to cause peripheral neuropathies, it is logical to question whether ED in OSA might reflect peripheral neuropathy resulting from the intermittent nocturnal hypoxia concomitant with OSA. Two recent studi...

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Erectile dysfunction in obstructive sleep apnea syndrome--prevalence and determinants.

INTRODUCTION OSAS (Obstructive Sleep apnea syndrome) is defined by recurrent episodes of upper airway obstruction during sleep, causing multiple clinical consequences. Literature review suggests that OSAS induces a spectrum of abnormalities in neural, hormonal and vascular regulation that contribute to the development of ED (erectile dysfunction). The aims of this study were to estimate the pre...

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Pure Obstructive Sleep Apnea Syndrome and Erectile Dysfunction

Objective: The aim of this study is to investigate the existence of erectile dysfunction in patients with obstructive sleep apnea syndrome (OSAS) in which the other possible causes of erectile dysfunction were eliminated. Material and Methods: The study group consisted of 24 patients diagnosed as OSAS with polysomnographic evaluation, and 15 non-apneic controls (mean age; 41.0±8.8 and 42.3±7.9 ...

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Erectile Dysfunction in Patients with Sleep Apnea – A Nationwide Population-Based Study

Increased incidence of erectile dysfunction (ED) has been reported among patients with sleep apnea (SA). However, this association has not been confirmed in a large-scale study. We therefore performed a population-based cohort study using Taiwan National Health Insurance (NHI) database to investigate the association of SA and ED. From the database of one million representative subjects randomly...

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ژورنال

عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine

سال: 2008

ISSN: 1073-449X,1535-4970

DOI: 10.1164/rccm.200801-190oc