ERGOTHIONEINE IN MICROORGANISMS
نویسندگان
چکیده
منابع مشابه
The biosynthesis of ergothioneine.
The recent finding that ergothioneine is synthesized by many common fungi (1) has led us to investigate the pathway of biosynthesis. In view of the relatively high concentrations of the substance found in Neurospuru crussa, this organism was selected for study. The results provide strong evidence to show that ergothioneine (I) is derived from hi&dine, that cysteine provides the sulfhydryl, grou...
متن کاملThe occurrence of ergothioneine in plant material.
The question of the synthesis of ergothioneine by animals has been investigated in this Laboratory by the administration of isotope-labeled compounds considered to be likely precursors. No evidence for the formation of radioactive ergothioneine was obtained with C14-histidine in the rat, methyl-labeled C14-methionine in the rat or chicken, S35-methionine in the rat, guinea pig, or pig, and S35-...
متن کاملDiscovery of the ergothioneine transporter.
Variants of the SLC22A4 gene are associated with susceptibility to rheumatoid arthritis and Crohn's disease. SLC22A4 codes for an integral membrane protein, OCTN1, that has been presumed to carry organic cations like tetraethylammonium across the plasma membrane. Here, we show that the key substrate of this transporter is in fact ergothioneine (ET). Human OCTN1 was expressed in 293 cells. A sub...
متن کاملProduction of ergothioneine by Methylobacterium species
Metabolomic analysis revealed that Methylobacterium cells accumulate a large amount of ergothioneine (EGT), which is a sulfur-containing, non-proteinogenic, antioxidative amino acid derived from histidine. EGT biosynthesis and its role in methylotrophy and physiology for plant surface-symbiotic Methylobacterium species were investigated in this study. Almost all Methylobacterium type strains ca...
متن کاملThe preparation and properties of ergothioneine disulphide.
Azouz, W. M., Parke, D. V. & Williams, R. T. (1952). Biochem. J. 50, 702. Carpenter, C. C., Shaffer, C. B., Weil, C. S. & Smyth, H. F. (1944). J. industr. Hyg. 26, 69. Danishefsky, I. & Wiilhite, M. (1954). J. biol. 'Chem. 211, 549. Eimhjellen, K. E. (1956). Biochem. J. 64, 4P. El Masri, A. M., Smith, J. N. & Williams, R. T. (1956). Biochem. J. 64, 50. Kamil, I. A., Smith, J. N. & Williams, R. ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1956
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)65113-0