Erratum: Can web 2.0 reboot clinical trials?
نویسندگان
چکیده
منابع مشابه
Evaluation of Clinical Trials
In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
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Evidence based medicine is very important for success of modern medicine. It is the ongoing process of using the most reliable evidence from clinical studies, scientific understanding and medical practice to make the best possible medical choice for patients. Evidence based medicine is how medicine advances and how we get improvements in life expectancy and quality of life. It not only identifi...
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Randomization plays a fundamental role in clinical trials. While many modern clinical trials employ restricted, stratifiedor covariate-adaptive randomization designs that pursue balance in treatment assignments and balance across important covariates, some clinical trials call for response-adaptive or covariate-adjusted response-adaptive (CARA) randomization designs to...
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Finding that an association is statistically insignificant in a clinical trial has two distinct explanations. (1) The association may be real, but the sample size is too small to distinguish the results from those due to chance. (2) The association is spurious – a coincidence due to chance. Based on Weisberg (2011), this paper argues that there is a third explanation: the association may be rea...
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The dried aerial parts of Hypericum perforatum, gathered during the flowering period or shortly before, are used medicinally. The generic name of the herb derives from the Greek meaning to ‘overcome an apparition’ and in earlier times homes would have a plant hanging over the door to ward off evil spirits. This species of hypericum (H. perforatum) is referred to as perforate St John’s wort due ...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2010
ISSN: 1087-0156,1546-1696
DOI: 10.1038/nbt0210-178f