Estimation of Fine-Scale Recombination Intensity Variation in the white–echinus Interval of D. melanogaster
نویسندگان
چکیده
منابع مشابه
Genome-Wide Fine-Scale Recombination Rate Variation in Drosophila melanogaster
Estimating fine-scale recombination maps of Drosophila from population genomic data is a challenging problem, in particular because of the high background recombination rate. In this paper, a new computational method is developed to address this challenge. Through an extensive simulation study, it is demonstrated that the method allows more accurate inference, and exhibits greater robustness to...
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15 صفحه اولSupporting Information Genome-wide fine-scale recombination rate variation in Drosophila melanogaster
Text S1 Two-locus recursion relation Suppose we sample n haplotypes, observing their alleles at each of two loci and obtaining configuration n = (a, b, c). Here c = (cij) is a matrix of the counts of haplotypes for which both alleles were observed; cij is the number of haplotypes with allele i at the first locus and allele j at the second locus. We also allow for the possibility that a haplotyp...
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ژورنال
عنوان ژورنال: Journal of Molecular Evolution
سال: 2009
ISSN: 0022-2844,1432-1432
DOI: 10.1007/s00239-009-9250-5