Estimation of genetic merit from bivariate « all or none » responses
نویسندگان
چکیده
منابع مشابه
From all to (nearly) none
The five adaptor protein (AP) complexes function in cargo-selection and coat-recruitment stages of vesicular transport in eukaryotic cells. Much of what we know about AP complex function has come from experimental work using Saccharomyces cerevisiae as a model. Here, using a combination of comparative genomic and phylogenetic approaches we provide evolutionary context for the knowledge gained f...
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Positive feedback loops and doublenegative feedback loops can generate bistability, allowing signaling networks to convert continuously graded inputs into discrete outputs [1–4]. One particularly well-studied bistable system consists of the mitotic regulator CDK1 with its inactivator Wee1 and its activator Cdc25 [5–7]. The system functions as a mitotic trigger, toggling between a stable interph...
متن کاملIndividual matching with multiple controls in the case of all-or-none responses.
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BACKGROUND GPRC6A, a widely expressed G-protein coupled receptor, is proposed to be a master regulator of complex endocrine networks and metabolic processes. GPRC6A is activated by multiple ligands, including osteocalcin (Ocn), testosterone (T), basic amino acids, and various cations. SCOPE OF REVIEW We review the controversy surrounding GPRC6A functions. In mice, GPRC6A is proposed to integr...
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Theories of probabilistic cognition postulate that internal representations are made up of multiple simultaneously held hypotheses, each with its own probability of being correct (henceforth, "probability distributions"). However, subjects make discrete responses and report the phenomenal contents of their mind to be all-or-none states rather than graded probabilities. How can these 2 positions...
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ژورنال
عنوان ژورنال: Génétique Sélection Évolution
سال: 1984
ISSN: 0754-0264
DOI: 10.1051/gse:19840304