Evaluating Methods to Correct for Population Stratification when Estimating Paternity Indexes
نویسندگان
چکیده
منابع مشابه
Evaluating Methods to Correct for Population Stratification when Estimating Paternity Indexes
The statistical interpretation of the forensic genetic evidence requires the use of allelic frequency estimates in the reference population for the studied markers. Differences in the genetic make up of the populations can be reflected in statistically different allelic frequency distributions. One can easily figure out that collecting such information for any given population is not always pos...
متن کاملTheoretical Formulation of Principal Components Analysis to Detect and Correct for Population Stratification
The Eigenstrat method, based on principal components analysis (PCA), is commonly used both to quantify population relationships in population genetics and to correct for population stratification in genome-wide association studies. However, it can be difficult to make appropriate inference about population relationships from the principal component (PC) scatter plot. Here, to better understand ...
متن کاملGenotype-based matching to correct for population stratification in large-scale case-control genetic association studies.
Genome-wide association studies are helping to dissect the etiology of complex diseases. Although case-control association tests are generally more powerful than family-based association tests, population stratification can lead to spurious disease-marker association or mask a true association. Several methods have been proposed to match cases and controls prior to genotyping, using family info...
متن کاملEvaluating the Methods of Estimating Potential Evapotranspiration in Omidiyeh Town
In order to determine the required water for irrigation it is necessary to calculate the amount of needed water by plant or evapotranspiration. The equations that are used to calculate evapotranspiration are not applying the same climatic parameters and, due to their experimental nature, they are not suitable for all climatic conditions. In the present study in order to compare evapotranspirati...
متن کاملUsing 15N Dilution Method to Correct for Microbial Contamination When Assessing in situ Protein Degradability of Fresh Ryegrass
This experiment was done to investigate microbial contamination and in situ disappearance rates of dry matter (DM), N and 15N of fresh labeled ryegrass. Perennial ryegrass (Lolium perenne) were labeled with 15N during growth in a glasshouse, harvested at 4th leaves stage and were incubated up to 34 h in situ in the rumen of 3 individually housed sheep. The animals were fed 800 g/d chopped alfal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0049832