Evaluation of an Enzyme Immunoassay Technique for Detection of Antibodies against Treponema pallidum
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چکیده
منابع مشابه
Evaluation of an enzyme immunoassay for IgM antibodies to Treponema pallidum in syphilis in man.
An enzyme immunoassay (EIA) for the detection of immunoglobulin M (IgM) antibodies to Treponema pallidum was investigated for specificity and sensitivity. Using the results in serum from 1192 patients with successfully treated syphilis, the assay was calculated to be about 97% specific. As in any other IgM enzyme linked immunosorbent assay (ELISA), rheumatoid factor played an important part in ...
متن کاملEvaluation of a new particle gel immunoassay for determination of antibodies against Treponema pallidum.
A new particle gel immunoassay (DiaMed AG, Cressier sur Morat, Switzerland) with three recombinant Treponema pallidum antigens was evaluated with serum samples from patients with syphilis (n = 124) and patients without syphilis (n = 490). It proved to be a simple, rapid (20 min), and useful test with sensitivity, specificity, and positive and negative predictive values of 91.9, 99.8, 99.2, and ...
متن کاملEvaluation of a Treponema pallidum enzyme immunoassay as a screening test for syphilis.
The CAPTIA Syphilis-G enzyme immunoassay for the detection of antibodies to Treponema pallidum was evaluated as a screening test for syphilis in comparison with the standard rapid plasma reagin (RPR) test. One thousand samples were tested, and the standard fluorescent treponemal antibody absorption test and the standard microhemmaglutination test were used to confirm the presence of treponemal ...
متن کاملStudies on Treponema Pallidum and Syphilis. Ii. Spiroch~ticidal Antibodies against Treponema Pallidum. by Hans
In a previous communication we have reported on the agglufinins which are formed in rabbits following systematic inoculation with concentrated culture material of Treponema pallidum. Incidentally it may be stated that a sheep has also been successfully used. The antigen used for the immunization of these animals was similar to that employed in the first agglutination experiments, except that we...
متن کاملValidation of Serological Tests for the Detection of Antibodies Against Treponema pallidum in Nonhuman Primates
There is evidence to suggest that the yaws bacterium (Treponema pallidum ssp. pertenue) may exist in non-human primate populations residing in regions where yaws is endemic in humans. Especially in light of the fact that the World Health Organizaiton (WHO) recently launched its second yaws eradication campaign, there is a considerable need for reliable tools to identify treponemal infection in ...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2003
ISSN: 0095-1137
DOI: 10.1128/jcm.41.1.250-253.2003