Evaluation of Oxidative Markers, Apoptosis and Reproductive Efficiency in Heroin Addicted Rats
نویسندگان
چکیده
منابع مشابه
Cerebellar neuronal apoptosis in heroin-addicted rats and its molecular mechanism.
BACKGROUND The overall objective of this study was to investigate neuronal apoptosis and expression of apoptosis related proteins (c-jun, cytc and Bax) in the cerebellum of rates with heroin addiction. MATERIAL/METHODS 40 adult male Sprague-Dawley rats which weighing 200-220 g were randomly divided into 5 groups (n = 8 per group): control group, 10-day heroin-addicted group, 20-day heroin-add...
متن کاملEvaluation of Enkephalin-Degrading Enzymes in Sperm from Heroin-Addicted Men
Objective The aim of this study was to investigate two enkephalin-degrading enzymes, aminopeptidase N (APN/CD13) and endopeptidase (NEP/CD10), gene and protein expression levels in sperm samples of fertile and heroin-addicted men, and the correlation between their expressions and semen quality. MaterialsAndMethods This case-control study, semen collected from 24 normozoospermic healthy (as a co...
متن کاملBehavior and development patterns in children born to heroin-addicted and methadone-addicted mothers.
This paper reviews the literature regarding the development of children up to age 6 years who were born to mothers addicted to heroin or methadone. These children are compared with children born to nonaddicted mothers to determine whether there were any differences between the two groups related to maternal drug addiction. This paper discusses the obstetrical and medical complications associate...
متن کاملGenetic variants associated with addictive behavior in Colombian addicted and non-addicted to heroin or cocaine
OBJECTIVE Determine the prevalence and compare some genetic markers involved in addictive behavior in a group of addicts to derivative of coca (cocaine/crack) or heroin and a control group of non-addicted people matched for gender, age and ethnicity. METHODS A 120 addicts and 120 non-addicts Colombian male were surveyed and genotyped for 18 polymorphism of the OPRM1, DRD2, DRD4, SLC6A3, SLC6A...
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ژورنال
عنوان ژورنال: IOSR Journal of Pharmacy (IOSRPHR)
سال: 2013
ISSN: 2319-4219,2250-3013
DOI: 10.9790/3013-031001-07