Evidence for Phase Opposition between Inner and Outer Hair Cells
نویسندگان
چکیده
منابع مشابه
Characterization of transcriptomes of cochlear inner and outer hair cells.
Inner hair cells (IHCs) and outer hair cells (OHCs) are the two types of sensory receptor cells that are critical for hearing in the mammalian cochlea. IHCs and OHCs have different morphology and function. The genetic mechanisms that define their morphological and functional specializations are essentially unknown. The transcriptome reflects the genes that are being actively expressed in a cell...
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6.1 The basics of wave propagation 6.1/a Effects of changes in standard parameters 6.2 Feedback between outer hair cells 6.2/a Feedback topology 6.2/b Response of three rows of cells 6.3 Modeling squirting wave excitation of the OHC array 6.3/a Explicit solution of the many-cell problem: full wavelength resonance Results and derivations 6.3/b Explicit solution of the many-cell problem: half-wav...
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Cochlear outer hair cells are postulated to modulate auditory transduction by their mechanical properties which presumably are controlled by efferent neurons and regulated by the levels of intracellular calcium. In a number of biological systems these calcium levels are controlled by inositol trisphosphate (InsP3), the second messenger of the phosphoinositide cascade. We have investigated wheth...
متن کاملSensory transduction and adaptation in inner and outer hair cells of the mouse auditory system.
Auditory function in the mammalian inner ear is optimized by collaboration of two classes of sensory cells known as inner and outer hair cells. Outer hair cells amplify and tune sound stimuli that are transduced and transmitted by inner hair cells. Although they subserve distinct functions, they share a number of common properties. Here we compare the properties of mechanotransduction and adapt...
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Regulation of gene expression is essential to determining the functional complexity and morphological diversity seen among different cells. Transcriptional regulation is a crucial step in gene expression regulation because the genetic information is directly read from DNA by sequence-specific transcription factors (TFs). Although several mouse TF databases created from genome sequences and tran...
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ژورنال
عنوان ژورنال: The Journal of the Acoustical Society of America
سال: 1974
ISSN: 0001-4966
DOI: 10.1121/1.3437948