Evolution and Design of Protein Structure by Folding Nucleus Symmetric Expansion
نویسندگان
چکیده
منابع مشابه
Evolution and design of protein structure by folding nucleus symmetric expansion.
Models of symmetric protein evolution typically invoke gene duplication and fusion events, in which repetition of a structural motif generates foldable, stable symmetric protein architecture. Success of such evolutionary processes suggests that the duplicated structural motif must be capable of nucleating protein folding. If correct, symmetric expansion of a folding nucleus sequence derived fro...
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ژورنال
عنوان ژورنال: Structure
سال: 2014
ISSN: 0969-2126
DOI: 10.1016/j.str.2014.08.008