Expanding the RNA alphabet: The expanding world of mRNA modifications

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The expanding world of primary adrenal insufficiencies.

The past few years have seen a phenomenal increase in our understanding of three genetic causes of primary adrenal and gonadal hormone deficiency. Lin and coworkers reported in 1995 (1) that patients with congenital lipoid adrenal hyperplasia have mutations of the steroidogenic acute regulatory protein. This protein has an essential role in the mobilization of cholesterol from lipid stores to t...

متن کامل

the tragedy of modern man in arthur millers world

what miller wants is a theatre of heightened consciousness. he speaks of two passions in a man, the passion to "feel" and the passion "know". he belives that we can have more of the latter. he says: drama is akin to the other inventions of man in that it ought to help us know more and not merely to spend our feelings. the writing of the crucible shows us that he is trying to give more heightene...

15 صفحه اول

Expanding a fluorescent RNA alphabet: synthesis, photophysics and utility of isothiazole-derived purine nucleoside surrogates.

A series of emissive ribonucleoside purine mimics, all comprised of an isothiazolo[4,3-d]pyrimidine core, was prepared using a divergent pathway involving a key Thorpe-Ziegler cyclization. In addition to an adenosine and a guanosine mimic, analogues of the noncanonical xanthosine, isoguanosine, and 2-aminoadenosine were also synthesized and found to be emissive. Isothiazolo 2-aminoadenosine, an...

متن کامل

Future of the World Oil Market with an Expanding Role of Shale Oil: A System Dynamics Approach

In this paper, we develop a dynamic system model to predict the effects of shale oil production on demand and supply of oil.  We study the interaction between demand and supply of OPEC and non-OPEC member countries and supply of shale oil, oil price, growth of the global economy, development of new oil reserves and  alternative energies. In our model, OPEC acts passively and covers the market d...

متن کامل

The dark matter rises: the expanding world of regulatory RNAs.

The ability to sequence genomes and characterize their products has begun to reveal the central role for regulatory RNAs in biology, especially in complex organisms. It is now evident that the human genome contains not only protein-coding genes, but also tens of thousands of non-protein coding genes that express small and long ncRNAs (non-coding RNAs). Rapid progress in characterizing these ncR...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The Biochemist

سال: 2016

ISSN: 0954-982X,1740-1194

DOI: 10.1042/bio03802013