Experimental Animal Models for Studies on the Mechanisms of Blast-Induced Neurotrauma
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چکیده
منابع مشابه
Experimental Animal Models for Studies on the Mechanisms of Blast-Induced Neurotrauma
A blast injury is a complex type of physical trauma resulting from the detonation of explosive compounds and has become an important issue due to the use of improvised explosive devices (IED) in current military conflicts. Blast-induced neurotrauma (BINT) is a major concern in contemporary military medicine and includes a variety of injuries that range from mild to lethal. Extreme forces and th...
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Although advances are being made in identifying some of the essential mechanisms that may lead to chronic neurological deficits after blast-exposure(s), clinical needs continue to exceed current knowledge. In their current article, Brenner and colleagues address the importance of basic science in guiding new diagnostic and treatment strategies. Together with Wilkinson et al., they emphasize one...
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Because insects had developed resistance to several insecticides, today, neonicotinoids and fiproles are used to combat pests. The difference between this two classes of insecticides is that fipronil acts by inhibiting the receptors of nervous cells, while neonicotinoids perturbs the neuronal transmission. The suitable properties of fipronil make that its use to be more obvious on the pesticide...
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A majority of investigations on primary blast injuries have focused on gas-containing organs, while the likelihood of blast-induced neurotrauma remains underrated. In Norway minke whales (Balaenoptera acutorostrata) are hunted using small fishing boats rigged with harpoon guns, which fire harpoons tipped with a grenade containing a charge of 30-g penthrite. The grenade detonates 60-70 cm inside...
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BACKGROUND With the onset of improved protective equipment against fragmentation, blast-induced neurotrauma has emerged as the "signature wound" of the current conflicts in the Middle East. Current research has focused on this phenomenon; however, the exact mechanism of injury and ways to mitigate the ensuing pathophysiology remain largely unknown. The data presented and literature reviewed for...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2012
ISSN: 1664-2295
DOI: 10.3389/fneur.2012.00030