Experimental Heterotopic Heart Transplantation: An Easier Technique
نویسندگان
چکیده
منابع مشابه
Murine Heterotopic Heart Transplant Technique
It is now over forty years since this technique was first reported by Corry, Wynn and Russell. Although it took some years for other labs to become proficient in and utilize this technique, it is now widely used by many laboratories around the world. A significant refinement to the original technique was developed and reported in 2001 by Niimi. Described here are the techniques that have evolve...
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INTRODUCTION More than 3 decades have passed since the first heterotopic heart transplantation (HHT) was reported. Nowadays, this surgical technique is used rarely, and only in patients who do not qualify for standard orthotopic heart transplantation (OHT). Current indications mainly comprise refractory pulmonary hypertension and a donor-recipient size mismatch (>20%). The objective of this stu...
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The heterotopic cervical heart transplantation in mice is a valuable tool in transplant and cardiovascular research. The cuff technique greatly simplifies this model by avoiding challenging suture anastomoses of small vessels thereby reducing warm ischemia time. In comparison to abdominal graft implantation the cervical model is less invasive and the implanted graft is easily accessible for fur...
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Introduction The current technique for heterotopic cardiac transplantation in patients with high pulmonary vascular resistance entails the interposition of a Dacron conduit1 between the native and donor pulmonary artery (PA) as it is not possible for the donor PA to reach the recipient PA (Figure 1). The original technique of Bernard and Losman2 was abandoned due to intractable arrhythmias. Da ...
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Transplant arteriosclerosis is the main limitation for long-term survival of solid organ transplant recipients. Animal models would provide invaluable tools to investigate the cellular and molecular mechanisms underlying the pathogenesis of transplant arteriosclerosis, as well as for studies with novel drugs and other reagents for the prevention of the disease. We have therefore developed a mod...
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ژورنال
عنوان ژورنال: European Surgical Research
سال: 2004
ISSN: 0014-312X,1421-9921
DOI: 10.1159/000075077