Exploiting immunometabolism and T cell function for solid organ transplantation
نویسندگان
چکیده
منابع مشابه
B Cell Immunity in Solid Organ Transplantation
The contribution of B cells to alloimmune responses is gradually being understood in more detail. We now know that B cells can perpetuate alloimmune responses in multiple ways: (i) differentiation into antibody-producing plasma cells; (ii) sustaining long-term humoral immune memory; (iii) serving as antigen-presenting cells; (iv) organizing the formation of tertiary lymphoid organs; and (v) sec...
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Desensitization protocols are being used worldwide to enable kidney transplantation across immunologic barriers, i.e. antibody to donor HLA or ABO antigens, which were once thought to be absolute contraindications to transplantation. Desensitization protocols are also being applied to permit transplantation of HLA mismatched hematopoietic stem cells to patients with antibody to donor HLA, to en...
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ژورنال
عنوان ژورنال: Cellular Immunology
سال: 2020
ISSN: 0008-8749
DOI: 10.1016/j.cellimm.2020.104068