Exploring protein sequence–function landscapes
نویسندگان
چکیده
منابع مشابه
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In this work we present a new method for investigating local energy minima on a protein energy landscape. The CABS (CAlpha, CBeta and the center of mass of the Side chain) method was employed for generating protein models, but any other method could be used instead. Cα traces from an ensemble of models are hierarchical clustered with the HCPM (Hierarchical Clustering of Protein Models) method. ...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2017
ISSN: 1087-0156,1546-1696
DOI: 10.1038/nbt.3786