Exploring tRNA gene cluster in archaea
نویسندگان
چکیده
منابع مشابه
Genes and pseudogenes in a reiterated rat tRNA gene cluster.
A 13.4 kb rat genomic DNA fragment containing two related tRNA gene clusters was isolated from a rat lambda recombinant and analyzed for gene arrangement and nucleotide sequence. One cluster was found to contain a tRNALeuCUG gene while the second contained a tRNALeuCUA pseudogene with multiple base substitutions. The tRNALeu gene was found to possess an intact coding region and a functional tra...
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A recent analysis of tRNA genes in Trypanosoma brucei has revealed an unusual genomic organisation where several genes encoding tRNAs and other small RNAs are very closely clustered (1). Genes encoding tRNA* (anticodon CUU) and tRNA^ (ACG) were found tightly linked to genes encoding a U snRNA (U RNA B, ref. 2) and a 275 nt RNA X of unknown function. At a separate genomic locus genes encoding tR...
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The gene-dense chromosomes of archaea and bacteria were long thought to be devoid of pseudogenes, but with the massive increase in available genome sequences, whole genome comparisons between closely related species have identified mutations that have rendered numerous genes inactive. Comparative analyses of sequenced archaeal genomes revealed numerous pseudogenes, which can constitute up to 8....
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The genomic sequences of Methanococcus jannaschii and Methanobacterium thermoautotrophicum contain a structurally uncommon seryl-tRNA synthetase (SerRS) sequence and lack an open reading frame (ORF) for the canonical cysteinyl-tRNA synthetase (CysRS). Therefore, it is not clear if Cys-tRNACys is formed by direct aminoacylation or by a transformation of serine misacylated to tRNACys. To address ...
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in a multistep process requiring ATP and GTP, leaving a 2Ј-phosphate at the splice junction. In a remarkable * Molecular Genetics Program Wadsworth Center final step, the phosphotransferase removes the 2Ј phosphate by transfer to NAD, generating a mature tRNA New York State Department of Health and School of Public Health with a standard 3Ј–5Ј linkage at the ligation junction Archaeal tRNA intr...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 2019
ISSN: 1678-8060,0074-0276
DOI: 10.1590/0074-02760180348