Expression of Disabled 1 suppresses astroglial differentiation in neural stem cells
نویسندگان
چکیده
منابع مشابه
Expression of Disabled 1 suppresses astroglial differentiation in neural stem cells.
Disabled 1 (Dab1), a cytoplasmic adaptor protein expressed predominantly in the CNS, transduces a Reelin-initiated signaling that controls neuronal migration and positioning during brain development. To determine the role of Dab1 in neural stem cell (NSC) differentiation, we established a culture of neurospheres derived from the embryonic forebrain of the Dab1(-/-) mice, yotari. Differentiating...
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ژورنال
عنوان ژورنال: Molecular and Cellular Neuroscience
سال: 2009
ISSN: 1044-7431
DOI: 10.1016/j.mcn.2008.08.012