Expression of keratinocyte growth factor receptor correlates with expansive growth and early stage of gastric cancer
نویسندگان
چکیده
منابع مشابه
Vascular endothelial growth factor (VEGF) receptor expression correlates with histologic grade and stage of colorectal cancer
BACKGROUND Colorectal carcinoma (CRC) is the seventh-most common malignancy and is the main cause of death in Iraq. The incidence of this cancer has increased sharply after the invasion of Iraq in 2003. AIM To estimate immunohistochemical expression of vascular endothelial growth factor (VEGF) in CRC in relation to other parameters, such as grade and stage of tumour. METHODS Formalin fixed,...
متن کاملAltered Expression of Epidermal Growth Factor Receptor (EGFR) in Glioma
EGFR is a key molecule in cancer cells. EGFR signaling was shown to promote tumor cell proliferation and survival, invasion and angiogenesis and mediate resistance to treatment, including ionizing radiation in preclinical models. We extracted proteins from astrocytoma (III and IV) oligodendroglioma(IV) tumors and normal brain tissues and then evaluated the protein purity by Bradford test ...
متن کاملKeratinocyte growth factor induces matrix metalloproteinase-9 expression and correlates with venous invasion in pancreatic cancer
Keratinocyte growth factor (KGF), also known as fibroblast growth factor-7, and KGF receptor (KGFR) play important roles in the growth of epithelial cells and are overexpressed in a variety of malignant epithelial tumors, including pancreatic ductal adenocarcinoma (PDAC). We previously reported that co-expression of KGF and KGFR in PDAC is associa...
متن کاملAZD2171 shows potent antitumor activity against gastric cancer over-expressing fibroblast growth factor receptor 2/keratinocyte growth factor receptor.
PURPOSE AZD2171 is an oral, highly potent, and selective vascular endothelial growth factor signaling inhibitor that inhibits all vascular endothelial growth factor receptor tyrosine kinases. The purpose of this study was to investigate the activity of AZD2171 in gastric cancer. EXPERIMENTAL DESIGN We examined the antitumor effect of AZD2171 on the eight gastric cancer cell lines in vitro and...
متن کاملEffect of One Time Irradiation of Uvb Non Keratinocyte Growth Factor Gene Expression in Mice
Purpose: Skin is continuously exposed to many hazardous environmental factors such as ultraviolet radiation (UV). Many investigations have been shown to cause skin damages. The aim of present research was to study the effect of a single time of UVB radiation on the expression pattern of keratinocyte growth factor (KGF) gene in mice. Materials and Methods: UVB (30 mJ/cm2 and 50 mJ/cm2) were rad...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Oncology
سال: 2006
ISSN: 1019-6439,1791-2423
DOI: 10.3892/ijo.28.2.307