Factor XI Deficiency: First Case Described in Algeria
نویسندگان
چکیده
منابع مشابه
Factor XI Deficiency in West Algeria: A Case Report and Literature Review
Factor XI deficiencies are rare. Initially, they were described only in Ashkenazy Jews with two types of characteristic gene mutation. Now, 152 mutations have been identified, mostly in non-Jewish population. We report the case of a deficiency identified in Arabic young girl living in West Algeria; gene sequences showed a type II mutation, frequent in Ashkenazy Jews. May be it is coincidence; b...
متن کاملFactor XI deficiency.
That factor XI has a role in normal blood coagulation is evidenced by the fact that patients with deficiency are prone to excessive bleeding after haemostatic challenge. The role of factor XI in physiological processes has become clearer since the discovery that it is activated by thrombin; this fact has contributed to a revised model of blood coagulation. Factor XI deficiency is particularly c...
متن کاملFactor XI activity and factor XI antigen in homozygous and heterozygous factor XI deficiency.
A relatively potent antiserum against highly purified, unactivated human factor XI antigen was raised in a rabbit. This antiserum, after concentration, neutralized 50% of the factor XI clotting activity of a standard normal plasma at an antiserum dilution of 1/900. The antiserum was used in a neutralization-inhibition assay to study the relation between factor XI clotting activity and factor XI...
متن کاملDominant Factor XI Deficiency Caused by Mutations in the Factor XI Catalytic Domain Running title: Autosomal dominant factor XI deficiency
(2497 articles) Hemostasis, Thrombosis, and Vascular Biology (1597 articles) Free Research Articles (3667 articles) Clinical Trials and Observations Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entirety may be found ...
متن کاملFactor XI deficiency--resolving the enigma?
The management of factor XI deficiency is not straightforward for three reasons: firstly, the role of this factor in the coagulation pathway is not clearly understood; secondly, the bleeding tendency, although mild, is unpredictable and does not clearly relate to the factor XI level; and thirdly, all treatment products, although available, have some potentially serious side effects. These facto...
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ژورنال
عنوان ژورنال: Journal of Blood Disorders & Transfusion
سال: 2015
ISSN: 2155-9864
DOI: 10.4172/2155-9864.1000s5-004