Fast filtering for RNA homology search

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Fast filtering for RNA homology search

MOTIVATION Homology search for RNAs can use secondary structure information to increase power by modeling base pairs, as in covariance models, but the resulting computational costs are high. Typical acceleration strategies rely on at least one filtering stage using sequence-only search. RESULTS Here we present the multi-segment CYK (MSCYK) filter, which implements a heuristic of ungapped stru...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2011

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/btr545