Feature Selection Methods for Early Predictive Biomarker Discovery Using Untargeted Metabolomic Data
نویسندگان
چکیده
منابع مشابه
Feature Selection Methods for Early Predictive Biomarker Discovery Using Untargeted Metabolomic Data
Untargeted metabolomics is a powerful phenotyping tool for better understanding biological mechanisms involved in human pathology development and identifying early predictive biomarkers. This approach, based on multiple analytical platforms, such as mass spectrometry (MS), chemometrics and bioinformatics, generates massive and complex data that need appropriate analyses to extract the biologica...
متن کاملStable feature selection for biomarker discovery
Feature selection techniques have been used as the workhorse in biomarker discovery applications for a long time. Surprisingly, the stability of feature selection with respect to sampling variations has long been under-considered. It is only until recently that this issue has received more and more attention. In this article, we review existing stable feature selection methods for biomarker dis...
متن کاملCombination of Feature Selection and Learning Methods for IoT Data Fusion
In this paper, we propose five data fusion schemes for the Internet of Things (IoT) scenario,which are Relief and Perceptron (Re-P), Relief and Genetic Algorithm Particle Swarm Optimization (Re-GAPSO), Genetic Algorithm and Artificial Neural Network (GA-ANN), Rough and Perceptron (Ro-P)and Rough and GAPSO (Ro-GAPSO). All the schemes consist of four stages, including preprocessingthe data set ba...
متن کاملFeature selection using genetic algorithm for classification of schizophrenia using fMRI data
In this paper we propose a new method for classification of subjects into schizophrenia and control groups using functional magnetic resonance imaging (fMRI) data. In the preprocessing step, the number of fMRI time points is reduced using principal component analysis (PCA). Then, independent component analysis (ICA) is used for further data analysis. It estimates independent components (ICs) of...
متن کاملBladder Cancer Biomarker Discovery Using Global Metabolomic Profiling of Urine
Bladder cancer (BCa) is a common malignancy worldwide and has a high probability of recurrence after initial diagnosis and treatment. As a result, recurrent surveillance, primarily involving repeated cystoscopies, is a critical component of post diagnosis patient management. Since cystoscopy is invasive, expensive and a possible deterrent to patient compliance with regular follow-up screening, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Molecular Biosciences
سال: 2016
ISSN: 2296-889X
DOI: 10.3389/fmolb.2016.00030