Female Germ Cell Development, Functioning and Associated Adversities under Unfavorable Circumstances

An investigation of primordial germ cell development in embryo and larvae of Huso huso

In sturgeons, Primordial Germ Cells originate from the vegetal pole of the egg. They migrate toward genital ridges during developmental stages and finally differentiate into gametes (the only cells that transmit genetic information). In this study, the cells were isolated from the place of migration of primordial germ cells in Huso huso’s larvae during two stages before and after absorption of ...

Necessity Entrepreneurship: Individual, Environmental and Public Policy-Related Factors Influencing the Process of Opportunity Exploitation under Unfavorable Circumstances

The topic of entrepreneurship, i.e. the process surrounding the identification and exploitation of opportunities by an individual, has received a great amount of interest from scholars throughout the last decades. Theoretical lenses from disciplines as varied as psychology, economics, strategy and sociology have been successfully employed in entrepreneurship research, greatly increasing our und...

Normal and malignant germ cell development.

Defining normal and malignant germ cell development is crucial for understanding the biology and behavior of germ cell tumors. Germ cell tumors show significant similarities with immature germ cells. Furthermore, treatment sensitivity of germ cell tumors reflects the intrinsic characteristics of the cell of origin, and their derivatives. The aim of this thesis was to identify factors involved i...

I-18: The Role of Sex Chromosomes in Female Germ Cell Differentiation

Background When gonadal sex reversal occurs in mammalian species, the resultant XX males and XY females become infertile or subfertile, suggesting critical roles of sex chromosomes in germ cell differentiation. The objective of our study is to clarify the mechanism of infertility in the B6.YTIR (XY) sex-reversed female mouse, which can be attributed to a failure in the second meiotic division i...

Signaling pathways in the development of female germ cells