First results about recovery of walking function in patients with intensive care unit-acquired muscle weakness from the General Weakness Syndrome Therapy (GymNAST) cohort study

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First results about recovery of walking function in patients with intensive care unit-acquired muscle weakness from the General Weakness Syndrome Therapy (GymNAST) cohort study

OBJECTIVES To describe the time course of recovery of walking function and other activities of daily living in patients with intensive care unit (ICU)-acquired muscle weakness. DESIGN This is a cohort study. PARTICIPANTS We included critically ill patients with ICU-acquired muscle weakness. SETTING Post-acute ICU and rehabilitation units in Germany. MEASURES We measured walking function...

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The General Weakness Syndrome Therapy (GymNAST) study: protocol for a cohort study on recovery on walking function

INTRODUCTION Critical illness myopathy (CIM) and polyneuropathy (CIP) are common complications of critical illness that frequently occur together. Both cause so called intensive care unit (ICU)-acquired muscle weakness. This weakness of limb muscles increases morbidity and delay rehabilitation and recovery of walking ability. Although full recovery has been reported people with severe weakness ...

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Intensive-care-unit-acquired muscle weakness.

Neuromuscular abnormalities culminating in skeletal-muscle weakness occur very commonly in critically ill patients. Intensive-care-unit (ICU) acquired neuromuscular abnormalities are typically divided into 2 discrete classes: polyneuropathy and myopathy. However, it is likely that these 2 entities commonly coexist, with myopathy being the most common cause of weakness. Major risk factors for IC...

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Intensive care unit acquired weakness : measuring recovery from critical illness

Introduction Intensive care unit-acquired weakness (ICU-AW) is a common consequence of critical illness, affecting between 25% and 100% of critical care patients.1,2 ICU-AW is a syndrome encompassing myopathic, neuropathic and atrophic changes, which clinically presents as profound weakness. Its presence can hinder and dictate the course of recovery, leading to protracted weaning from mechanica...

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Clinical review: intensive care unit acquired weakness.

A substantial number of patients admitted to the ICU because of an acute illness, complicated surgery, severe trauma, or burn injury will develop a de novo form of muscle weakness during the ICU stay that is referred to as "intensive care unit acquired weakness" (ICUAW). This ICUAW evoked by critical illness can be due to axonal neuropathy, primary myopathy, or both. Underlying pathophysiologic...

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ژورنال

عنوان ژورنال: BMJ Open

سال: 2015

ISSN: 2044-6055,2044-6055

DOI: 10.1136/bmjopen-2015-008828