Fixed-dose combination versus separate drug formula for pulmonary and extrapulmonary tuberculosis
نویسندگان
چکیده
منابع مشابه
Treatment outcomes of fixed-dose combination versus separate tablet regimens in pulmonary tuberculosis patients with or without diabetes in Qatar
BACKGROUND Tuberculosis is considered the second most common cause of death due to infectious agent. The currently preferred regimen for treatment of pulmonary tuberculosis (PTB) is isoniazid, rifampin, pyrazinamide, and ethambutol, which has been used either as separate tablets (ST) or as fixed-dose combination (FDC). To date, no studies have compared both regimens in Qatar. We aim to evaluate...
متن کاملEfficacy and safety of a four-drug fixed-dose combination regimen versus separate drugs for treatment of pulmonary tuberculosis: a systematic review and meta-analysis
INTRODUCTION Tuberculosis, particularly multi-drug-resistant tuberculosis, is a major cause of morbidity and mortality worldwide. To the best of our knowledge, however, no study to date has assessed the combined use of the four available drugs for tuberculosis treatment, which is an issue of great clinical relevance. OBJECTIVE To determine whether the four-drug fixed-dose combination is safer...
متن کاملFixed dose drug combination for treatment of tuberculosis.
877 VOLUME 46__OCTOBER 17, 2009 Anti-tuberculosis therapy (ATT) with multiple antimicrobials, administered individually or as fixed dose combinations (FDC) is the key to control of tuberculosis. Arguments in favour of FDC include better patient compliance, simplification of prescriptions, easier management of drug supply, reduced programmatic cost, and less chances of developing drug resistance...
متن کاملComparison of the safety and efficacy of a fixed-dose combination regimen and separate formulations for pulmonary tuberculosis treatment
OBJECTIVES Fixed-dose combination formulations, which simplify the administration of drugs and prevent the development of drug resistance, have been recommended as a standard anti-tuberculosis treatment regimen. However, the composition and dosage recommendations for fixed-dose combination formulations differ from those for separate formulations. Thus, questions about the effectiveness and side...
متن کاملFixed-dose combinations of drugs versus single-drug formulations for treating pulmonary tuberculosis
BACKGROUND People who are newly diagnosed with pulmonary tuberculosis (TB) typically receive a standard first-line treatment regimen that consists of two months of isoniazid, rifampicin, pyrazinamide, and ethambutol followed by four months of isoniazid and rifampicin. Fixed-dose combinations (FDCs) of these drugs are widely recommended. OBJECTIVES To compare the efficacy, safety, and acceptab...
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ژورنال
عنوان ژورنال: Egyptian Journal of Bronchology
سال: 2018
ISSN: 1687-8426,2314-8551
DOI: 10.4103/ejb.ejb_61_17