Flow cytometric reticulocyte maturity index: A useful laboratory parameter of erythropoietic activity in anemia
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چکیده
منابع مشابه
Reticulocyte hemoglobin: an integrated parameter for evaluation of erythropoietic activity.
Traditional reticulocyte counts provide only a partial estimate of the erythropoietic bone marrow activity and do not account for qualitative variations of reticulocyte cellular indexes and hemoglobin content in particular. We have studied a new integrated parameter, reticulocyte hemoglobin (retHb), that quantifies in grams per liter the hemoglobin contained in the circulating reticulocyte comp...
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We performed a flow cytometric (FCM) analysis of the maturity of reticulocytes using peripheral blood obtained from rats administered 5-fluorouracil (5-FU) at 10, 50 and 100 mg/kg or acethylphenyl hydrazine (APHZ) at 1 and 3 mg/kg to clarify whether the FCM method is useful for assessing toxicity. In the 5-FU-administered rats, a decrease and recovery of the immature reticulocyte fraction (Cell...
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By ALLAN J. EIISLEV D ILUTION ANEMIA 011 HYDIIE\IIA is a condition characterized by an increase in total plasma volume without corresponding change in total red cell volume. Certain anemias complicating pregnancy,’ malnutrition,2 netirasthenia,3 and the t.herapetttic use of phenylbutazone4 and steroids5 have been considered to he caused by such a dilution of the red cell mass. The erythropoieti...
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Hepcidin, the principal iron regulatory hormone, regulates the absorption of iron from the diet and the mobilization of iron from stores. Previous studies indicated that hepcidin is suppressed during anemia, a response that would appropriately increase the absorption of iron and its release from stores. Indeed, in the mouse model, hepcidin-1 was suppressed after phlebotomy or erythropoietin adm...
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ژورنال
عنوان ژورنال: Cytometry
سال: 1995
ISSN: 0196-4763,1097-0320
DOI: 10.1002/cyto.990220107