Fluorescence imaging of ATP in neutrophils from patients with sepsis using organelle-localizable fluorescent chemosensors
نویسندگان
چکیده
منابع مشابه
Fluorescence imaging of ATP in neutrophils from patients with sepsis using organelle-localizable fluorescent chemosensors
BACKGROUND The activation of polymorphonuclear neutrophils (PMNs) plays an important role in sepsis. Previously, we showed that ATP release and feedback via ATP receptors are essential for PMN activation; however, the dynamics remain poorly understood. Two new fluorescent chemosensors, PMAP-1 and MitoAP-1, were developed to detect ATP in the plasma membrane and mitochondria of living cells, res...
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ژورنال
عنوان ژورنال: Annals of Intensive Care
سال: 2016
ISSN: 2110-5820
DOI: 10.1186/s13613-016-0175-z